Technology

Minicircle DNA – mcDNA – platform technology

minimal expression cassette

circular covalently closed – supercoiled – DNA vector

free of bacterial elements

minicircles are optimized DNA vectors for gene therapy or DNA vaccination with critically improved overall efficiency designed for clinical applications. mcDNA is a supercoiled minimal expression cassette free of bacterial backbone elements (antibiotic markers, CpG motifs, origin of replication), the most promising non-viral vector technology.

Our mcDNA platform provides:

  • Industrial scalability
  • GMP conform production

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